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Chemistry of Natural Compounds

, Volume 9, Issue 1, pp 88–89 | Cite as

Solid-phase synthesis of the partially protected A13–21 fragment of insulin

  • G. A. Korshunova
  • G. P. Mishin
  • Yu. P. Shvachkin
Article
  • 19 Downloads

Summary

Using the solid-phase method, the synthesis has been effected of a partially protected A13–21 fragment of insulin and of analogs of this fragment: the hydrobromides of H-Leu-Tyr-GlN-Leu-Glu-AsN-Tyr-Cys(Bzl)-AsN-OH, H-Ala-Tyr-GlN-Leu-Glu-AsN-Tyr-Cys(Bzl)-AsN-OH and H-Leu-Tyr-Ala-Leu-Glu-Ala-Tyr-Cys(Bzl)-AsN-OH.

Keywords

Dioxane Asparagine Amino Acid Analysis Anisole Hydrobromide 

Literature cited

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    R. B. Merrifield, J. Amer. Chem. Soc.,86, 304 (1964).CrossRefGoogle Scholar
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    R. B. Merrifield, Biochemistry,3, 1385 (1964).CrossRefGoogle Scholar
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    G. A. Korshunova, G. P. Mishin, Yu. A. Semiletov, N. A. Voskova, and Yu. P. Shvachkin, Khim. Prirodn. Soedin., 799 (1971).Google Scholar

Copyright information

© Consultants Bureau, a division of Plenum Publishing Corporation 1975

Authors and Affiliations

  • G. A. Korshunova
  • G. P. Mishin
  • Yu. P. Shvachkin

There are no affiliations available

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