Chemistry of Natural Compounds

, Volume 9, Issue 1, pp 79–81 | Cite as

Lysine- and arginine-containing polypeptides of regular structure and their bactericidal properties

  • G. F. Kasymova
  • V. K. Burichenko
  • É. E. Meitus
  • K. T. Poroshin


1. Polypeptides of regular structure with the amino acid sequences (-Gly-L-Ala-L-Arg-), (-L-Lys-L-Arg-L-Ala-), (-L-Lys-L-Arg-Gly) have been synthesized.

2. It has been established that the polypeptide (-Gly-L-Ala-L-Arg) possesses a bactericidal action which exceeds that of the known polypeptide (-L-Leu-L-Orn-Leu-).


Bactericidal Property Regular Structure Gramicidin DMFA Benzyloxycarbonyl 


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Literature cited

  1. 1.
    L. Bichowsky-Slomnicki, A. Berger, Y. Kurtz, and E. Katchalski, Arch. Biochem. Biophys.,65, 400 (1956).CrossRefGoogle Scholar
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    M. Fridkin, A. Frenkel, and S. Ariely, Biopolymers,8, No. 5, 661 (1969).CrossRefGoogle Scholar
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    G. F. Kasymova, V. K. Burichenko, K. T. Poroshin, and M. B. Berdyeva, Dokl. Akad. Nauk TadzhSSR,13, No. 10, 25 (1970).Google Scholar

Copyright information

© Consultants Bureau, a division of Plenum Publishing Corporation 1975

Authors and Affiliations

  • G. F. Kasymova
  • V. K. Burichenko
  • É. E. Meitus
  • K. T. Poroshin

There are no affiliations available

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