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Transferrins in the metabolism of iron

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Abstract

The main physicochemical characteristics of the transferrins, their physiological role, and questions of reticulocyte-transferrin interaction and the biosynthesis of transferrin are discussed.

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Literature cited

  1. L. Heilmeyer, in: Iron Metabolism, an International Symposium, F. Gross, ed., Springer, Berlin (1964), p. 201.

    Google Scholar 

  2. R. E. Feeney and S. K. Komatsu, Struct. Bond. (Berlin),1, 149 (1966).

    Google Scholar 

  3. D. Harris and P. Aisen, J. Biol. Chem.,249, 5261 (1975).

    Google Scholar 

  4. P. L. Masson, J. F. Heremans, and Ch. Dive, Clin. Chem. Acta,14, 735 (1966).

    Google Scholar 

  5. P. L. Masson and J. F. Heremans, Comp. Biochem. Physiol.,39, 119 (1971).

    Google Scholar 

  6. G. A. Annenkov, The Proteins of Primate Blood Serum [in Russian], Moscow (1974).

  7. M. Pollycove, Hemochromatosis (1972), p. 1051.

  8. E. H. Morgan, in: Iron in Biochemistry and Medicine, Academic Press, New York (1974), p. 30.

    Google Scholar 

  9. B. Blanc and A. Vanotti, Nature (London),212, 480 (1966).

    Google Scholar 

  10. T. G. Saakashvili, Collection from the Institute of Urology and Nephrology of the GSSR [in Russian] (1980).

  11. A. D. Dzhalov and V. A. Maksimov, Ter. Arkh.,54, No. 2, 57–59 (1982).

    Google Scholar 

  12. Ch. S. Jurado, C. I. Nunez, and R. J. Moralara, Laboratorio,72, No. 434, 145 (1982).

    Google Scholar 

  13. Krzalic and N. Kastrapeli, Period. Biologorum,83, No. 3, 315 (1981).

    Google Scholar 

  14. M. Pollycove, in: The Metabolic Basis of Inherited Disease, 2nd edn., McGraw-Hill, New York (1966).

    Google Scholar 

  15. R. R. Crichton, Struct. Bond.,17, 67 (1973).

    Google Scholar 

  16. E. H. Morgan, Med. J. Aust.,2, 322 (1972).

    Google Scholar 

  17. J. Fletcher and E. R. Huehns, Nature (London),218, 1211 (1968).

    Google Scholar 

  18. J. Fletcher and E. R. Huehns, Nature (London),215, 584 (1967).

    Google Scholar 

  19. J. H. Jandl and J. H. Katz, J. Clin. Invest.,42, 267 (1970).

    Google Scholar 

  20. G. Cartei and A. Meani, Nutr. Rep. Int.,2, 267 (1970).

    Google Scholar 

  21. G. Alderton, W. H. Ward, and H. L. Fevold, Arch. Biochem.,11, 9 (1946).

    Google Scholar 

  22. M. L. Groves, J. Am. Chem. Soc.,82, 3345 (1960).

    Google Scholar 

  23. A. Bezkorovainy, 179th ACS National Meeting, Houston, Tex., Abstr. Pap. Washington (1980), p. 146.

  24. M. Cappeletti and G. Cavadini, Tecn. Sanit.,13, No. 5, 351 (1975).

    Google Scholar 

  25. K. G. Mann, W. W. Fish, A. S. Cox, and C. Tanford, Biochemistry,9, 1348 (1970).

    Google Scholar 

  26. C. A. Jamieson, J. Biol. Chem.,240, 2914 (1965).

    Google Scholar 

  27. G. Spic, B. Fournet, B. Baynard, G. Strecker, S. Bouquelet, and J. Montreuil, FEBS Lett.,50, 296 (1975).

    Google Scholar 

  28. F. C. Greene and R. E. Feeney, Biochemistry,7, 1366 (1968).

    Google Scholar 

  29. D. Harris and P. Aisen, Biochemistry,14, No. 2, 262 (1975).

    Google Scholar 

  30. B. Teuwissen, P. L. Masson, P. Osinski, and J. F. Heremans, Eur. J. Biochem.,31, 239 (1972).

    Google Scholar 

  31. C. K. Luk, Biochemistry,10, 2838 (1971).

    Google Scholar 

  32. R. C. Sephton and A. W. Harris, J. Natl. Cancer Inst.,54, 1263 (1975).

    Google Scholar 

  33. D. C. Harris, G. A. Gray, and P. Aisen, J. Biol. Chem.,249, 526 (1974).

    Google Scholar 

  34. A. Gafni and I. Z. Streinberg, Biochemistry,13, 800 (1974).

    Google Scholar 

  35. L. K. White and Chasteen, in press.

  36. G. W. Bates and M. R. Schlabach, in: Proteins of Ion Transport in Biochemistry and Medicine, R. R. Crichton, ed., North-Holland, Amsterdam (1975).

    Google Scholar 

  37. B. R. Gaber and P. Aisen, Biochim. Biophys. Acta,221, 228 (1970).

    Google Scholar 

  38. G. W. Bates, E. F. Workman, and M. R. Schlabach, Biochem. Biophys. Res. Commun.,50, 84 (1973).

    Google Scholar 

  39. R. M. Palmour and M. E. Sutton, Biochemistry,10, 4026 (1971).

    Google Scholar 

  40. G. W. Bates and M. R. Schlabach, FEBS Lett.,33, 289 (1973).

    Google Scholar 

  41. G. W. Bates and M. R. Schlabach, J. Biol. Chem.,250, 2177 (1975).

    Google Scholar 

  42. E. M. Price and J. F. Gibson, Biochem. Biophys. Res. Commun.,46, 646 (1972).

    Google Scholar 

  43. G. W. Bates and G. Graham, in: Iron and Copper Proteins, K. T. Yasunobu, H. F. Mower, and O. Haiyashi, eds., Plenum Press, New York (1976), p. 400.

    Google Scholar 

  44. P. Aisen, R. Aasa, G. B. Malmstrom, and T. Vanngard, J. Biol. Chem.,248, 2484 (1967).

    Google Scholar 

  45. R. E. Feeny and S. K. Komatsu, Struct. Bond.,1, 149, 206 (1964).

    Google Scholar 

  46. J. M. Kinkade, W. W. Miller, and F. M. Segars, Biochim. Biophys. Acta,446, 407 (1976).

    Google Scholar 

  47. A. Hekman, Biochim. Biophys. Acta,251, 380 (1971).

    Google Scholar 

  48. J. Williams, Biochem. J.,83, 355 (1962).

    Google Scholar 

  49. J. Williams, Biochem. J.,83, 355 (1962).

    Google Scholar 

  50. D. C. Lee, G. S. McKnight, and R. D. Palmiter, J. Biol. Chem.,253, No. 10, 3494 (1978).

    Google Scholar 

  51. B. Blans, E. Bujard, and J. Mauron, Experimenta,19, 299 (1963).

    Google Scholar 

  52. J. Montreuil, J. J. Tonnelat, and S. Mullet, Biochim. Biophys. Acta,45, 413 (1960).

    Google Scholar 

  53. A. Bezkorovainy and D. Grolich, Arch. Biochem. Biophys.,107, 303 (1973).

    Google Scholar 

  54. G. A. Jamieson, J. Biol. Chem.,240, 2914 (1965).

    Google Scholar 

  55. G. A. Jamieson, Biochim. Biophys. Acta,121, 326 (1966).

    Google Scholar 

  56. L. Doriand, J. Haverkamp, B. L. Schult, J. F. G. Vlingenthart, G. Spic, G. Strecker, B. Fournet, and J. Montreuil, FEBS Lett.,77, 15 (1977).

    Google Scholar 

  57. K.-A. Karlsson, I. Pascher, B. E. Sounvelsson, J. Finne, T. Krusius, and H. Rauvala, FEBS Lett.,94, 413 (1978).

    Google Scholar 

  58. G. A. Jamieson, M. Jett, and S. L. DeBernardo, J. Biol. Chem.,246, 3686 (1971).

    Google Scholar 

  59. R. T. A. MacGillivray, E. Mendez, S. K. Sinha, M. R. Sutton, J. Linebak-Zins, and K. Brew, Proc. Natl. Acad., Sci. USA, Biol. Sci.,79, No. 8, 2504 (1982).

    Google Scholar 

  60. I. Graham and J. Williams, Biochem. J.,145, 263 (1975).

    Google Scholar 

  61. G. Aschwell and A. G. Morell, Adv. Enzymol.,41, 99 (1974).

    Google Scholar 

  62. G. Spik and J. M. Mazurier, Ref. Zh.,28, 143 (1977).

    Google Scholar 

  63. D. K. Struck, P. B. Siuta, M. D. Lane, and W. J. Lennarz, J. Biol. Chem.,253, 5332 (1978).

    Google Scholar 

  64. J. H. Brock and F. R. Arzabe, FEBS Lett.,69, No. 1, 63 (1976).

    Google Scholar 

  65. R. M. Butterworth, J. F. Gibson, and J. Williams, Biochem. J.,149, 559 (1975).

    Google Scholar 

  66. W. M. Keung, P. Azari, and J. L. Phillips, J. Biol. Chem.,257, No. 3, 1177 (1982).

    Google Scholar 

  67. A. A. Buglanov and T. A. Salikhov, Khim. Prir. Soedin., 768 (1983).

  68. R. T. A. MacGillivray and K. Brew, Science,190, No. 4221, 1360 (1975).

    Google Scholar 

  69. M. H. Metz-Boutique, J. Jolles, J. Mazurier, G. Spic, J. Montreuil, and P. Jolles, Biochimie,60, No. 5, 557 (1978).

    Google Scholar 

  70. J. Williams, T. C. Elleman, J. B. Kingston, A. G. Wilkins, and K. A. Kuhn, Eur. J. Biochem.,122, No. 2, 297 (1982).

    Google Scholar 

  71. J. M. Jeltsch and P. Chambon, Eur. J. Biochem.,122, 291 (1982).

    Google Scholar 

  72. M. M. Metz-Boutique et al., Biochim. Biophys. Acta,670, No. 2, 243 (1981).

    Google Scholar 

  73. W. M. Keung, P. Azari, and L. Phillips, J. Biol. Chem.,257, No. 3, 1177 (1982).

    Google Scholar 

  74. D. Strickland and B. G. Hudson, Biochemistry,17, No. 16, 3411 (1978).

    Google Scholar 

  75. J. H. Brock and F. B. Arzabe, FEBS Lett.,69, No. 1, 63 (1976).

    Google Scholar 

  76. W. M. Keung and P. Azari, J. Biol. Chem.,257, No. 3, 1184 (1982).

    Google Scholar 

  77. J. Williams, S. A. Grace, and J. M. Williams, Biochem. J.,201, No. 2, 417 (1982).

    Google Scholar 

  78. J. Fletcher and E. R. Huehns, Nature (London),215, 584 (1967).

    Google Scholar 

  79. M. Azari, B. Chopman, and E. B. Brown, Clin. Res.,20, 784 (1972).

    Google Scholar 

  80. M. Awei, B. Chipman, and E. B. Brown, J. Lab. Clin. Med.,86, 576 (1975).

    Google Scholar 

  81. E. B. Brown, S. Okada, M. Awai, and B. Chipman, J. Lab. Clin. Med.,86, 576 (1975).

    Google Scholar 

  82. F. Fletcher, Clin. Sci.,37, 273 (1969).

    Google Scholar 

  83. R. S. Lane, Br. J. Haematol.,24, 343 (1973).

    Google Scholar 

  84. J. Fletcher and E. R. Heuhns, Nature,218, 1211 (1968).

    Google Scholar 

  85. J. Williams, Biochem. J.,149, No. 1, 237 (1975).

    Google Scholar 

  86. D. C. Harris and P. Aisen, Nature (London),257, 821 (1975).

    Google Scholar 

  87. D. C. Harris, Biochim. Biophys. Acta,496, 563 (1977).

    Google Scholar 

  88. H. Huebers, E. Huebers, E. Csiba, and C. A. Finch, J. Clin. Invest.,62, No. 5, 944 (1978).

    Google Scholar 

  89. J. V. Princiotto and E. J. Zapolski, Biochim. Biophys. Acta,428, 766 (1976).

    Google Scholar 

  90. S. Okada, B. Jarvis, and E. B. Brown, J. Lab. Clin. Med.,93, No. 2, 189 (1979).

    Google Scholar 

  91. M. Awai, B. Chipman, and E. B. Brown, J. Lab. Clin. Med.,85, 769 (1975).

    Google Scholar 

  92. N. J. Verhoef, M. J. Kottenhagen, H. J. M. Mulder, P. J. Noordeloos, and B. Leijanse, Acta Haematol.,60, 210 (1978).

    Google Scholar 

  93. J. H. Jandl and J. H. Katz, J. Clin. Invest.,42, 314 (1963).

    Google Scholar 

  94. R. S. Lane, Biochim. Biophys. Acta,243, 193 (1971).

    Google Scholar 

  95. M. Y. Rosseneu-Montreff, F. Soetewey, R. Lamote, and H. Peeters, Biopolymers,10, 1039 (1971).

    Google Scholar 

  96. A. Bezkorovainy, Biochim. Biophys. Acta,127, 535 (1966).

    Google Scholar 

  97. P. A. Charlwood, Biochem. J.,125, 1019 (1971).

    Google Scholar 

  98. P. Aisen, R. Aasa, G. B. Malmstrom, and T. Vanngard, J. Biol. Chem.,248, 2484 (1967).

    Google Scholar 

  99. G. W. Bates and G. Graham, in: Iron and Copper Proteins, K. T. Yasunobu, H. F. Mower, and O. Haiyashi, eds., Plenum Press, New York (1976).

    Google Scholar 

  100. G. W. Bates and M. R. Schlabach, J. Biol. Chem.,150, 2177 (1975).

    Google Scholar 

  101. P. Aisen, R. A. Pinkowitz, and A. Liebman, Ann. N.Y. Acad. Sci.,222, 337 (1973).

    Google Scholar 

  102. A. Egged, Biochim. Biophys. Acta,411, 349 (1975).

    Google Scholar 

  103. S. C. Williams and R. C. Woodworth, J. Biol. Chem.,248, 5848 (1973).

    Google Scholar 

  104. P. Aisen and A. Liebman, Biochim. Biophys. Acta,304, 797 (1973).

    Google Scholar 

  105. P. Aisen and E. B. Brown, Semin. Hematol.,14, 31 (1977).

    Google Scholar 

  106. J. Martinex-Medellin and L. Benavides, Biochim. Biophys. Acta,584, 84 (1979).

    Google Scholar 

  107. S. G. Kailis and E. H. Morgan, Biochim. Biophys. Acta,464, 389 (1977).

    Google Scholar 

  108. J. H. Jandl, J. K. Inman, R. L. Simmons, and D. W. Allen, J. Clin. Invest.,38, 161 (1959).

    Google Scholar 

  109. P. Aisen and A. Liebman, Bioinorg. Chem.,1, 116 (1977).

    Google Scholar 

  110. N. E. Garrett, R. J. Garrett, and J. W. Archdeacon, Biochem. Biophys. Res. Commun.,52, 466 (1977).

    Google Scholar 

  111. J. Fielding and B. E. Speyer, Biochim. Biophys. Acta,363, 387 (1974).

    Google Scholar 

  112. D. P. Witt and R. C. Woodworth, in: Proteins of Iron Storage and Transport in Biochemistry and Medicine, R. R. Crichton, ed., North-Holland, Amsterdam (1975), p. 133.

    Google Scholar 

  113. C. Schneider, R. Sutherland, R. Newman, and M. Greaves, J. Biol. Chem.,257, 8516 (1982).

    Google Scholar 

  114. J. H. Jandl and J. H. Katz, J. Clin. Invest.,42, 314 (1963).

    Google Scholar 

  115. E. F. Workman and G. W. Bates, in: Proteins of Iron Storage and Transport Biochemistry and Medicine, R. R. Crichton, ed., North-Holland, Amsterdam (1975), p. 155.

    Google Scholar 

  116. A. Sullivan and J. Grasso, Blood,47, No. 1, 133 (1976).

    Google Scholar 

  117. S. Kornfeld, Biochim. Biophys. Acta,194, 25 (1969).

    Google Scholar 

  118. B. J. Iacopetta, E. H. Morgan, and G. C. T. Yech, Biochim. Biophys. Acta,687, No. 2, 204 (1982).

    Google Scholar 

  119. E. H. Morgan, J. Biol. Chem.,244, No. 7, 4193 (1969).

    Google Scholar 

  120. D. C. Lee, G. S. McKnight, and R. D. Palmiter, J. Biol. Chem.,253, No. 10, 3494 (1978).

    Google Scholar 

  121. S. N. Thibodeau, D. C. Lee, and R. D. Palmiter, J. Biol. Chem.,253, No. 11, 3771 (1978).

    Google Scholar 

  122. N. E. Hynes et al., Biochemistry,18, No. 4, 616 (1979).

    Google Scholar 

  123. V. S. Gaitskhoki, N. A. Timchenko, L. T. Timchenko, L. E. Puckhova, Kh. A. Aslanov, and T. A. Salikhov, Biokhimiya,46, No. 8, 1426 (1981).

    Google Scholar 

  124. V. S. Gaitskhoki, N. A. Timchenko, L. T. Timchenko, L. V. Fuchkova, Kh. A. Aslanov, and T. A. Salikhov, Biokhimiya,47, No. 1, 13 (1982).

    Google Scholar 

  125. S. A. Neifakh, T. D. Aleinikova, V. S. Gaitskhoki, N. K. Monakhov, and L. V. Puchkova, Dokl. Akad. Nauk SSSR,244, No. 1, 238 (1979).

    Google Scholar 

  126. G. Schrieber, Col. Ges. Biol. Chem.,30, 50 (1979).

    Google Scholar 

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Institute of Bioorganic Chemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 139–151, March–April, 1984.

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Salikhov, T.A., Buglanov, A.A. Transferrins in the metabolism of iron. Chem Nat Compd 20, 129–140 (1984). https://doi.org/10.1007/BF00579469

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