Acylation of steroid alcohols with 3-carboxypropanamido acids
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Using N-(3-carboxypropanoyl)-β-phenyl-α-alanine as a model it has been established that when steroid alcohols are esterified with 3-carboxypropanamido acids, the carboxy group of the succinic acid residue takes part in the esterification reaction. In order to obtain a steroid ester of a 3-carboxypropanamido acid in which the carboxyl of the amino acid is the esterifying group, the carboxy group of the succinic acid residue must first be esterified.
KeywordsAlanine Acid Chloride Carboxy Group Thionyl Chloride Dihydrotestosterone
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- 1.J. Cason, Org. Synth., Coll. Vol. III, 169–171 (1955).Google Scholar