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Malignant fibroxanthoma (malignant histiocytoma): an ill-defined histologic entity with unpredictable biologic behavior

Report of a case with long-term survival

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Summary

The case of a 45-year-old woman with malignant fibroxanthoma (malignant histiocytoma) of the abdominal wall is reported. A local recurrence five years after surgery and radiation therapy required removal. Subsequent surgical intervention for radionecrosis and a fecal fistula failed to reveal residual tumor; the patient is free of tumor twenty-five years after the initial excision. The differential diagnosis of atypical and malignant fibroxanthoma is discussed. Studies of the small number of malignant fibroxanthomas reported in the literature suggest a poor correlation of the histopathologic characteristics of these lesions with their relatively benign biologic behavior.

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Authors and Affiliations

  1. Department of Pathology and Department of Surgery of the University of Kiel, Germany

    K. Küchemann & G. Waschulzik

Authors
  1. K. Küchemann
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  2. G. Waschulzik
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Küchemann, K., Waschulzik, G. Malignant fibroxanthoma (malignant histiocytoma): an ill-defined histologic entity with unpredictable biologic behavior. Virchows Arch. Abt. A Path. Anat. 350, 389–393 (1970). https://doi.org/10.1007/BF00578545

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  • DOI: https://doi.org/10.1007/BF00578545

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