The clinical investigator

, Volume 72, Issue 12, pp 1060–1064 | Cite as

Two cases of neurologigal manifestations in eosinophilia: variations of one disease?

  • S. Ostrowitzkil
  • S. Zierz
Case Reports


The hypereosinophilic syndrome is characterized by a long-lasting increase in circulating eosinophils in the absence of a definable etiology and by manifestations of multisystem involvement. It must be differentiated from the eosinophiliamyalgia syndrome related to the ingestion of L-tryptophan, although the clinical features may be similar. Two patients with hypereosinophilia not related to L-tryptophan intake are described who both became clinically symptomatic with neurological manifestations of acute and subacute onset: one with eosinophilic fasciitis and the other with painful polyneuropathy. Both responded well to corticosteroids.

Key words

Hypereosinophilic syndrome Eosinophilic fasciitis Polyneuropathy Eosinophiliamyalgia syndrome 



computed tomography


hypereosinophilic syndrome


eosinophilic-myalgia syndrome


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Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • S. Ostrowitzkil
    • 1
  • S. Zierz
    • 2
  1. 1.Neurologische Universitätsklinik BonnBonnGermany
  2. 2.Neurologische Universitätsklinik Halle-WittenbergHalle/ScaleGermany

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