Summary
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1.
In stages 5 and 6 ofHamburger andHamilton, the presumptive heart primordia of both sides, placed in contact, Fig. 1, originate two hearts in many cases instead of joining and originating a unique heart, as happens during normogenesis.
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2.
The two hearts are independent and are found to be very close in the same pericardial cavity, Figs. 7 and 8.
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3.
The heart formed, from the primordium left “in situ”, is a complete and normal heart, Figs. 7 and 8.
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4.
The heart formed from the transplant is much smaller and consists of a bulb, ventricle, and in some cases atrium, but its curvatures are typical and normal, Figs. 7 and 8.
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5.
The heart formed of the transplant organizes itself in contact with a small foregut formed from the endoderm of the transplant, Figs. 4 and 9.
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6.
The endoderm ist not only important in order for the P.H.M. to begin its differentiation in a heart direction but also organizes the P.H.M in such a way that the result is not only heart tissue but a heart, i.e. an organ with typical form and structure.
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Llorca, F.O. What are the factors which lead to the fusion of the two heart primordia ? An experimental analysis. W. Roux' Archiv f. Entwicklungsmechanik 155, 437–450 (1964). https://doi.org/10.1007/BF00577652
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DOI: https://doi.org/10.1007/BF00577652