Chemistry of Natural Compounds

, Volume 19, Issue 6, pp 639–657 | Cite as

Bioglycans as immunomodulators

  • Yu. S. Ovodov
  • R. G. Ovodova
  • Yu. N. Loenko


A review is given of facts relating to the search for and study of bioglycan immunomodulators which are polysaccharides and glycoconjugates of natural origin and possess the capacity for stimulating or inhibiting the immunity of Man and animals to various diseases. The structural-chemical characteristics and biological properties of the following classes of bioglycan immunomodulators are discussed: bacterial lipopolysaccharides and peptidoglycans of marine organisms. Particular attention is devoted to marine invertebrates as an important source of active bioglycan immunomodulators. On the basis of information that has been accumulated on this question, it is suggested that the capacity for producing bioglycans with pronounced immunostimulating activity is a common property of marine invertebrates.


Polysaccharide Antitumoral Activity Glucan Marine Invertebrate Yeast Cell Wall 


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© Plenum Publishing Corporation 1984

Authors and Affiliations

  • Yu. S. Ovodov
  • R. G. Ovodova
  • Yu. N. Loenko

There are no affiliations available

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