Chemistry of Natural Compounds

, Volume 20, Issue 4, pp 475–478 | Cite as

Polypeptides possessing catalytic properties

  • Sh. Kh. Khalikov
  • S. V. Alieva
  • R. V. Valiev


The catalytic properties of synthetic polypeptides containing L-amino acids with the sequences H-(His-Glu)n-OH, H-(Ser-Glu)n-OH, H-(His-Tyr)n-OH, and H-(Trp-Glu)n-OH in the hydrolysis of p-NPA (para-nitrophenyl acetate) are considered. The dependences of the rates of the polypeptide-catalyzed hydrolysis of p-NPA on the pH of the medium, the temperature, and the concentration of p-NPA are discussed. Vmax, Km, and K″ — the effective rate constants of the hydrolysis of p-NPA — and K2 — the constant for the splitting out of p-nitrophenol from the substrate — have been found and calculated.


Polypeptide Chymotrypsin Cotton Seed Effective Rate Constant Synthetic Polypeptide 


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Copyright information

© Plenum Publishing Corporation 1985

Authors and Affiliations

  • Sh. Kh. Khalikov
  • S. V. Alieva
  • R. V. Valiev

There are no affiliations available

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