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A study of the mechanism of action of colchicine on embryos ofMicrohyla ornata

  • B. A. Diwan
Article

Summary

  1. 1.

    The effect of colchicine on developmental stages ofMicrohyla ornata has been studied.

     
  2. 2.

    Treatment with colchicine at early neurula stage (stage 14–15) has no effect on development.

     
  3. 3.

    Treatment with colchicine at early stages of development caused 1. Suppression of gastrulation, 2. Oedema, 3. Microcephaly, 4. Eye defects and 5. loss of pigmentation.

     
  4. 4.

    The effects of colchicine could be completely reversed by subsequent treatment with cysteine hydrochloride (2.5 μg/ml).

     
  5. 5.

    The possible modes of action of colchicine have been discussed.

     

Keywords

Cysteine Developmental Stage Hydrochloride Developmental Biology Colchicine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag 1967

Authors and Affiliations

  • B. A. Diwan
    • 1
  1. 1.Department of ZoologyUniversity of PoonaIndia

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