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Das Säure-Basen-Gleichgewicht des Kammerwassers in Abhängigkeit von Kohlendioxid- und Sauerstoff-Diffusion durch die Cornea

Article

Zusammenfassung

An 20 Kaninchen ist der Einfluß des Gaswechsels über die Hornhaut zwischen Kammerwasser und umgebender Luft auf das Säure-Basen-Gleichgewicht im Kammerwasser untersucht worden. Es ließ sich zeigen, daß ein dichter Lidverschluß zu einer Erhöhung des Kohlendioxid-Partialdruckes sowie zu einer Verminderung des Sauerstoff-Partialdruckes im Kammerwasser führt; gleichzeitig läßt sich eine Verschiebung im Säure-Basen-Gleichgewicht des Kammerwassers im Sinne einer gemischten Form der Azidose (respiratorische und metabolische Azidose) nachweisen.

The dependence of acid-base balance in the aqueous humor on carbon dioxide and oxygen diffusion through the cornea

Abstract

In 20 rabbits the effect of, gas exchange, between the aqueous humor and surrounding air through the cornea, on the acid-base balance in the aqueous was investigated. It was found that tight eye closure leads to a decrease of oxygen partial pressure in the aqueous humor. A concurrent displacement of the acid-base balance in the form of a mixed acidosis (respiratory and metabolic acidosis) was demonstrated.

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Literatur

  1. 1.
    Barr RE., Hennessey M, Murphy VG (1977) Diffusion of Oxygen at the endothelial surface of the rabbit cornea. J Physiol (London) 270:1–8Google Scholar
  2. 2.
    Barr RE, Roetman EL (1974) Oxygen gradients in the anterior chamber of antesthetized rabbits. Invest. Ophthal. 13 (5): 386–388Google Scholar
  3. 3.
    Barr RE, Silver IA (1973) Effects of corneal environment on Oxygen tension in the anterior chambers of rabbits. Invest Ophthal 12:140–144Google Scholar
  4. 4.
    Fatt I, Bieber MT (1968) The steady-state distribution of Oxygen and carbon dioxyde in the in vivo cornea. I The open eye in air and the closed eye Exp Eye Res 7:103–112Google Scholar
  5. 5.
    Fatt I., Freeman RD, Lin D (1974) Oxygen tension distributions in the cornea: A re-examination. Exp Eye Res 18:357–365Google Scholar
  6. 6.
    Freeman RD (1972) Oxygen consumption by the component layers of the cornea. J Physiol 225:15–32Google Scholar
  7. 7.
    Freeman RD, Fatt I (1972) Oxygen permeability of the limiting layers of the cornea. Biophys J 12:237–247Google Scholar
  8. 8.
    Heald D, Langham ME (1956) Permeability of the cornea and the blood-aqueous barrier to Oxygen. Br J Ophthal 40:705–720Google Scholar
  9. 9.
    Van Heyningen R (1965) The metabolism of glucose by the rabbit lens in the presence and absence of Oxygen. Biochem J 96:419Google Scholar
  10. 10.
    Hill RM, Fatt I (1963) Oxygen uptake from a reservior of limited volume by the human cornea in vivo. Science NY 142:1295–1297Google Scholar
  11. 11.
    Kwan M, Niinikoski J, Hunt TK (1972) In vivo measurements of Oxygen tension in the cornea, aqueous humour and anterior lens of the open eye. Invest Ophthal11, (2): 108–114Google Scholar
  12. 12.
    Langham ME (1952) Utilization of Oxygen by the component layers of the living cornea. J Physiol 117:461–470Google Scholar
  13. 13.
    Riley MV (1969) Glucose and Oxygen utilization by the rabbit cornea. Exp Eye Res 8:193–200Google Scholar

Copyright information

© Springer-Verlag 1980

Authors and Affiliations

  • E. Gamm
    • 1
  1. 1.Laboratorium f. PathophysiologieHelmholtz-Institut f. AugenerkrankungenMoskauUSSR

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