Advertisement

Studies into cerebrospinal acid base values in intensive care patients

  • N. Buchanan
  • R. D. Cane
Article

Abstract

CSF acid base homeostasis was studied in 22 patients in an Intensive Care Unit, to ascertain whether an assessment of this parameter was of any prognostic value. The only significant findings were a lower CSF bicarbonate concentration in those patients who demised, as well as a poor correlation between CSF pH and both CSF PCO2 and bicarbonate. It was concluded that an assessment of CSF acid base balance was of no prognostic value in this particular group of patients.

Key words

Cerebrospinal fluid acid base balance Prognostic value 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Plum, R.: Ion homeostasis in cisternal and lumbar cerbrospinal fluid. New Engl. J. Med. 293, 1041 (1975)Google Scholar
  2. 2.
    Posner, J. B., Swanson, A. G., Plum, F.: Acid base in cerebrospinal fluid. Arch. Neurol. 12, 479 (1965)Google Scholar
  3. 3.
    Buchanan, N., Eyberg, C.: Acid base balance of cerebrospinal fluid in acute uncompensated metabolic acidosis of infancy. S. Mr. Med. J. 48, 1471 (1974)Google Scholar
  4. 4.
    Lipschitz, R.: Ph. D. Thesis. University of the Witwatersrand 1975Google Scholar
  5. 5.
    Buchanan, N., Eyberg, C.: Exercises with a blood gas analyzer. S. Afr. Med. J. 47, 1757 (1973)Google Scholar
  6. 6.
    Mitchell, R. A., Herbert, D. A., Carman, C. T.: Acid base constants and temperature coefficients for cerebrospinal fluid. J. appl. Physiol. 20, 443 (1965)Google Scholar
  7. 7.
    Davson, H.: Physiology of the cerebrospinal fluid. London: Churchill 1967Google Scholar
  8. 8.
    van Heijst, A. N. P., Maas, A. H. J., Visser, B. F.: Comparison of the acid base balance in cisternal and lumbar cerebrospinal fluid. Pflügers Arch. 287, 242 (1966)Google Scholar
  9. 9.
    Leusen, I.: Regulation of CSF composition with reference to breathing. Physiol Rev. 52, 1 (1972)Google Scholar

Copyright information

© Springer-Verlag 1976

Authors and Affiliations

  • N. Buchanan
    • 1
    • 2
  • R. D. Cane
    • 1
  1. 1.Intensive Care UnitBaragwanath HospitalJohannesburgSouth Africa
  2. 2.Metabolic UnitBaragwanath HospitalS. Africa

Personalised recommendations