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Action of alkaline solutions of hydroxamic acids on guanylic acid and RNA

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It has been shown that at pH 10 and 37° C, hydroxamine acids do not react directly with any of the components of ribonucleic acid. Under these conditions the cleavage of the polynucleotide chain takes place at an appreciable rate.

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References

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Khimiya Prirodnykh Soedinenii, Vol. 4, No. 4, pp. 230–232, 1968

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Kochetkov, N.K., Budovskii, E.I. & Domkin, V.D. Action of alkaline solutions of hydroxamic acids on guanylic acid and RNA. Chem Nat Compd 4, 197–198 (1968). https://doi.org/10.1007/BF00571135

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  • DOI: https://doi.org/10.1007/BF00571135

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