, Volume 88, Issue 3–6, pp 641–643 | Cite as

Genetic variation as a tool for histochemical localization of a nonspecific esterase

  • O. H. von Deimling
Short Communications


A prominent esterase activity was demonstrated histochemically in the straight portion of the proximal tubules in kidney of the mouse strain DBA/2J after inhibition with bis-p-nitrophenyl phosphate and subsequent staining, using 5-bromoindoxyl acetate as substrate. In the strain PUC/1Fre, the corresponding esterase was only weakly expressed. By comparing data from the literature (von Deimling et al. 1981) with the characteristic features of this kidney esterase including substrate preference, sensitivity to inhibitors, solubility, histochemical location, and strain differences, it was concluded that it was identical with the previously electrophoretically defined esterase-16.


Public Health Phosphate Acetate Genetic Variation Characteristic Feature 
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Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • O. H. von Deimling
    • 1
  1. 1.Ludwig-Aschoff-Haus, Pathologisches Institut der Universität FreiburgFreiburgFederal Republic of Germany

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