Chemistry of Natural Compounds

, Volume 4, Issue 6, pp 304–309 | Cite as

The structure of perforine and haplophyllidine

  • Z. Sh. Faizutdinova
  • I. A. Bessonova
  • S. Yu. Yunusov
Article
  • 24 Downloads

Conclusions

1. The alkaloids perforine and haplophyllidine isolated from the seeds ofH. perforatum have the developed formulas C16H17N(OH)2(OCH3)2(-O-) and C16H16N(OH) (OCH3)2(-O-).

2. Perforine is 7-hydroxy-8-(3′-hydroxy-3′-methylbutyl)-4, 8-dimethoxy-5, 6, 7, 8-tetrahydrofuroquinoline, and haplophyllidine is 7-hydroxy-4, 8-dimethoxy-(3′-methyl-2′-butenyl)-5, 6, 7, 8-tetrahydrofuroquinoline.

3. The transition from perforine to haplophyllidine has been effected by the splitting off of hydrogen chloride from chloroacetylperforine.

Keywords

Glacial Acetic Acid Hydroxy Group Methoxy Group Furan Ring Acetyl Chloride 

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Copyright information

© The Faraday Press, Inc 1971

Authors and Affiliations

  • Z. Sh. Faizutdinova
    • 1
  • I. A. Bessonova
    • 1
  • S. Yu. Yunusov
    • 1
  1. 1.Institute of the Chemistry of Plant Substances, AS UzSSRUSSR

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