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Ribosomal proteins

XIX. Altered S5 ribosomal protein in anEscherichia coli revertant from streptomycin dependence to independence

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Summary

Ribosomal proteins fromE. coli mutant N421 which is a spontaneous revertant from streptomycin dependence to independence have been compared to those of the wild type by two-dimensional polyacrylamide gel electrophoresis and by four immunochemical methods. The only detectable difference is a change in protein S5. This finding suggests that reversion from streptomycin dependence to independence can be caused not only by a mutation in protein S4, as described earlier, but also in protein S5.

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Communicated by P. Starlinger

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Stöffler, G., Deusser, E., Wittmann, H.G. et al. Ribosomal proteins. Molec. Gen. Genet. 111, 334–341 (1971). https://doi.org/10.1007/BF00569785

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