Human Genetics

, Volume 60, Issue 2, pp 172–175 | Cite as

Of rabbit and man: Comparative gene mapping

  • Joëlle Soulie
  • J. de Grouchy
Original Investigations

Summary

Nineteen cell hybrids were obtained by fusing rabbit (Oryctolagus cuniculus, OCU) fibroblasts and a Chinese hamster cell line HGPRT. Eleven enzymatic markers were investigated for cosegregation analysis. Seven could be assigned to OCU chromosomes: LDHA to OCU1; LDHB and TPI to OCU4; PEPB, NP, and ITP to OCU16; and G6PD to OCUX. Two assignments were considered possible: MDH2 to OCU15, and GUK to OCU3 or 15. Two could not be assigned: MDH1 and PGD. These results are consistent with the OCU-HSA chromosome homocologies previously reported, except for PEPB.

Keywords

Internal Medicine Gene Mapping Metabolic Disease Cell Hybrid Enzymatic Marker 

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Copyright information

© Springer-Verlag 1982

Authors and Affiliations

  • Joëlle Soulie
    • 1
    • 2
  • J. de Grouchy
    • 1
    • 2
  1. 1.E.R. 149 C.N.R.S.Hôpital Necker-Enfants-MaladesParís Cedex 15France
  2. 2.U. 173 I.N.S.E.R.M.Hôpital Necker-Enfants-MaladesParís Cedex 15France

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