Summary
The frequency of variants in the Pb system was studied in 71 individuals from the Bozo tribe in the Bani-Niger area (Mali, West Africa), in 25 male students from different African countries, and in 110 Dutch students. The frequency of thePb 2allele was 0.20 in the Bozo and 0.00 in the Dutch population. A comparison is made with the results of a study among American blacks and with a Japanese study. The Pb2-2 phenotypes observed in this study favour the hypothesis that the Pb-2c protein is derived from a larger precursor in a manner analogous to the generation of the Pb-1b protein from Pb-1 proteine.
References
Ananthakrishnan, R.: Polymorphismen aus Speichel, Urin und Milch: Basische Speichelproteine. In: Humangenetik, I/3, P. E. Becker (ed.), pp. 601–604. Stuttgart: Thieme 1975
Azen, E. A.: Genetic polymorphism of basic protein from parotid saliva. Science176, 673–674 (1972)
Azen, E. A.: Properties of salivary basic proteins showing polymorphism. Biochem. Genet.9, 69–85 (1973)
Curby, W. A.: Device for collection of human parotid saliva. J. Lab. Clin. Med.41, 493–496 (1953)
Minaguchi, K., Ikemoto, S., Nakajima, I., Susuki, K.: Studies of genetic markers in human saliva. I. Frequencies of Pa and Pb systems from parotid saliva from Japanese in Tokyo. Bull. Tokyo Dent. Coll.17, 185–190 (1976)
Peeters, E. H., Azen, E. A.: Isolation and partial characterization of human parotid basic proteins. Biochem. Genet.15, 925–946 (1977)
Reed, T. A.: Caucasian genes in American negroes. Science165, 762–767 (1969)
Sung, M., Smithies, O.: Differential elution of histones from gel-trapped nuclei. Biopolymers7, 39–58 (1969)
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Part of this work was performed in the Institute of Human Biology, State University at Utrecht, The Netherlands
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Pals, G., Pronk, J.C. Genetic variation in parotid basic proteins (Pb) in the Bozo (Mali, West Africa). Hum Genet 49, 355–359 (1979). https://doi.org/10.1007/BF00569356
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DOI: https://doi.org/10.1007/BF00569356