Abstract
Restriction endonuclease fragment length variations (RFLVs) were detected by using a rat cDNA probe for the bilirubin UDP-glucuronosyltransferase (UDPGT) gene between two mouse strains, 129/Sv and MOL-MIT. RFLVs of the gene were found byEcoRI andPvuII digestions. From linkage analyses of the three-point cross test usingElo andEn-1 as marker genes, the bilirubin UDPGT gene was mapped at position 37 on chromosome 1. Bilirubin and phenol UDPGTs have been suggested to be expressed by a single gene by alternative splicing in human and rat. The mouse bilirubin UDPGT gene was namedGnt-1.
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This study was supported by Grant-in-Aid for Research Project A-II from the Institute for Developmental Research, Aichi Prefecture Colony.
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Sato, H., Sakai, Y., Koiwai, O. et al. Mapping of the mouse bilirubin UDP-glucuronosyltransferase gene (Gnt-1) to chromosome 1 by restriction fragment length variations. Biochem Genet 30, 347–352 (1992). https://doi.org/10.1007/BF00569325
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DOI: https://doi.org/10.1007/BF00569325