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Xanthoma secondary to Reticulo-Histiocyte infiltration

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Summary

Three cases of xanthomas occurring secondarily are reported: The primary dermatoses were erythroderma, actinic reticuloid and histiocytosis X. Although a slight elevation of pre-β-lipoprotein was recognized, xanthomas occurring in these particular 3 cases were assumed to be due to the proliferation or hyperplasia of reticulohistiocytes in the skin. The foam cells found in the xanthoma case with erythroderma and actinic reticuloid appeared different from those with histiocytosis X in their fine structures. The lipid constituents of the xanthoma lesion were found to be quite dissimilar from those of serum lipids.

Zusammenfassung

Es wird über 3 Fälle mit sekundär aufgetretenen Xanthomen berichtet: Die primären Dermatosen sind Erythrodermie, actinisches Reticuloid und Histiocytosis X. Xanthome bei diesen 3 Fällen sind der Proliferation oder Hyperplasie des Reticuloendothelialsystems in der Haut zuzuschreiben, obgleich eine geringe Steigerung von Pre-β-Lipoprotein vorhanden ist. Die Feinstruktur der Schaumzellen in den Xanthomen bei den Fällen mit Erythrodermie und actinischem Reticuloid sind verschieden von denjenigen bei Histiocytosis X. Die Lipidbestandteile der xanthomatösen Läsion sind völlig verschieden von denen der Serumlipide.

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Authors and Affiliations

  1. Department of Dermatology, Tohoku University School of Medicine, Seiryomachi 1-1, Japan

    Akihiko Sato, Yoshio Tanahashi & Okitaka Maie

  2. Department of Third Internal Medicine, Tohoku University School of Medicine, 980 Sendai, Seiryomachi 1-1, Japan

    Yoshiaki Maruhama

Authors
  1. Akihiko Sato
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  2. Yoshio Tanahashi
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  3. Okitaka Maie
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  4. Yoshiaki Maruhama
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Sato, A., Tanahashi, Y., Maie, O. et al. Xanthoma secondary to Reticulo-Histiocyte infiltration. Arch. Derm. Res. 257, 93–106 (1976). https://doi.org/10.1007/BF00569118

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  • DOI: https://doi.org/10.1007/BF00569118

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