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Chemistry of Natural Compounds

, Volume 7, Issue 3, pp 325–332 | Cite as

A study of the conformational states of cyclopeptide systems

VI. Infrared spectra and dipole moments of the diastereomeric cyclohexaalanyls
  • V. T. Ivanov
  • L. B. Senyavina
  • E. S. Efremov
  • V. V. Shilin
  • Yu. A. Ovchinnikov
Article

Summary

1. An empirical method for the quantitative determination of the number of NH groups of different types in peptides based on measurements of the integral intensity of the amide A bands in the IR spectra has been developed.

2. The IR spectra of the diastereomeric cyclohexaalanyls in CHCl3 solutions have been studied; they indicate the participation of an average of four NH groups in IMBHs.

3. On the basis of a theoretical conformational analysis and of dipole-moment measurements, the system of IMHBs and the type of dominant conformation of the cyclohexapeptides in nonpolar solvents have been established.

Keywords

Dipole Moment Nonpolar Solvent Valinomycin Potential Energy Minimum Conformational Equilibrium 

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Copyright information

© Consultants Bureau, a division of Plenum Publishing Corporation 1973

Authors and Affiliations

  • V. T. Ivanov
  • L. B. Senyavina
  • E. S. Efremov
  • V. V. Shilin
  • Yu. A. Ovchinnikov

There are no affiliations available

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