Chemistry of Heterocyclic Compounds

, Volume 18, Issue 7, pp 740–745 | Cite as

Catalytic synthesis of diazines from 1,3-diaminopropane and 3-amino-1-propanol

  • Ya. F. Oshis
  • A. A. Anderson
  • M. V. Shimanskaya
Article
  • 43 Downloads

Abstract

The transformations of 1,3-diaminopropane and 3-amino-1-propanol under pulse conditions over tungsten trioxide in an inert atmosphere at 300–500 °C were investigated. The transformation of 1,3-diaminopropane leads to the formation of saturated pyrimidine bases; the maximum selectivity of the formation of hexahydropyrimidine bases at 300 °C is 60%, while the selectivity of the formation of tetrahydropyrimidine bases is 20% (400 °C). In the case of 3-amino-1-propanol the overall yield of heterocyclic bases was less than 5%, and piperazine and pyrazine derivatives were observed as the cyclic products; the formation of pyrimidine bases was not observed.

Keywords

Atmosphere Organic Chemistry Tungsten Pyrimidine Inert Atmosphere 

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Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • Ya. F. Oshis
    • 1
  • A. A. Anderson
    • 1
  • M. V. Shimanskaya
    • 1
  1. 1.Institute of Organic SynthesisAcademy of Sciences of the Latvian SSRRiga

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