Chemistry of Natural Compounds

, Volume 9, Issue 4, pp 492–497 | Cite as

Olivomycin and related antibiotics XXX. The structure of chromocyclin

  • Yu. A. Berlin
  • M. N. Kolosov
  • I. V. Severtsova


1. The glycoside chromocyclomycin has been isolated from the culture liquid ofStreptomyces LA-7017, and its aglycone, chromocyclin, has been obtained.

2. As a result of degradation and the results of a comparison with the properties of model compounds, structure (I) has been established for chromocyclin.


Ethyl Acetate Anhydrotetracycline Deacetyl Acetic Acid Lead Olivomycin 


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Literature cited

  1. 1.
    Yu. A. Berlin, M. N. Kolosov, I. V. Vasina, and I. V. Yartseva, Chem. Commun., 762 (1968).Google Scholar
  2. 2.
    Yu. A. Berlin, E. F. Boldyreva, M. N. Kolosov, G. P. Pronina, V. S. Soifer, and I. V. Yartseva, Khim. Prirodn. Soedin., 542 (1972).Google Scholar
  3. 3.
    Yu. A. Berlin, O. A. Kiseleva, M. N. Kolosov, V. D. Kuznetsov, E. I. Lupach, I. V. Severtsova, G. M. Smirnova, V. S. Soifer, and I. V. Yartseva, Khim. Prirodn. Soedin., 537 (1972).Google Scholar
  4. 4.
    A. Albert and E. Serjeant, Ionization Constants of Acids and Bases, Methuen (1962).Google Scholar
  5. 5.
    F. A. Hochstein, M. Schach von Wittenau, F. W. Tanner, and K. Murai, J. Amer. Chem. Soc.,82, 5934 (1960).CrossRefGoogle Scholar
  6. 6.
    M. N. Kolosov, S. A. Popravko, V. G. Korobko, M. G. Karapetyan, and M. M. Shemyakin, Zh. Obshch. Khim.,34, 2547 (1964).Google Scholar
  7. 7.
    C. R. Stephens, L. H. Conover, R. Pasternack, F. A. Hochstein, W. T. Moreland, P. P. Regna, F. J. Pilgrim, K. T. Brunings, and R. B. Woodward, J. Amer. Chem. Soc.,76, 3568 (1954).CrossRefGoogle Scholar
  8. 8.
    J. R. D. McCormick, in: Antibiotics, D. Gottlieb and P. D. Shaw (editors), Springer, New York, Vol. II (1967), p. 113.Google Scholar
  9. 9.
    L. A. Mitscher, J. V. Juvarkar, W. Rosenbrook, W. W. Andres, J. Schenck, and R. S. Egan, J. Amer. Chem. Soc.,92, 6070 (1970).CrossRefGoogle Scholar
  10. 10.
    V. I. Frolova, A. D. Kuzovkov, and G. S. Rozenfel'd, Antibiotiki,11, 298 (1966).Google Scholar

Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • Yu. A. Berlin
  • M. N. Kolosov
  • I. V. Severtsova

There are no affiliations available

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