Chemistry of Natural Compounds

, Volume 7, Issue 5, pp 608–610 | Cite as

The structure of folisine

  • I. A. Bessonova
  • S. Yu. Yunusov


  1. 1.

    From the mixture of alkaloids ofH. foliosum has been isolated a new base — folisine — which is 1-methyl-α,β-dihydrofurano-4-quinolone with a substituting group on the α-carbon atom.

  2. 2.

    The transition from dubinidine to folisine has been effected by the reaction of dubinidine methiodide with anhydrous pyridine.

  3. 3.

    When dubinidine is heated with methyl iodide in a sealed tube, the usual isomerization takes place and folisine is formed.



Alkaloid Periodic Acid Methyl Iodide Seal Tube Methiodide 


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Literature cited

  1. 1.
    D. Kurbanov, I. A. Bessonova, and S. Yu. Yunusov, Khim. Prirodn. Soedin.,4, 373 (1968).Google Scholar
  2. 2.
    H. Rapoport and K. G. Holden, J. Amer. Chem. Soc.,82, 4395 (1960).CrossRefGoogle Scholar
  3. 3.
    J. A. Bosson, M. Rasmussen, et al., Austr. J. Chem.,16, 480 (1963).CrossRefGoogle Scholar
  4. 4.
    I. A. Bessonova and S. Yu. Yunusov, Khim. Prirodn. Soedin.,5, 29 (1969).Google Scholar
  5. 5.
    R. A. Corral and O. O. Orazi, Tetrahedron,21, 909 (1965).CrossRefGoogle Scholar
  6. 6.
    G. Reisch, K. Szendrei, E. Minker, and I. Novak, Pharmazie,24, 699 (1969).PubMedGoogle Scholar
  7. 7.
    I. A. Bessonova, Z. Sh. Faizutdinova, Ya. V. Rashkes, and S. Yu. Yunusov, Khim. Prirodn. Soedin.,6, 446 (1970).Google Scholar
  8. 8.
    G. P. Sidyakin, M. Eskairov, and S. Yu. Yunusov, Zh. Obshch. Khim.,30, 338 (1960).Google Scholar
  9. 9.
    R. H. F. Manske and H. L. Holmes, The Alkaloids: Chemistry and Physiology, Academic Press, New York, Vol. 3 (1953), p. 72.Google Scholar
  10. 10.
    R. M. Bowman and M. F. Grundon, J. Chem. Soc., C,1966, 1504.Google Scholar

Copyright information

© Consultants Bureau 1974

Authors and Affiliations

  • I. A. Bessonova
  • S. Yu. Yunusov

There are no affiliations available

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