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Advances in the chemistry of biotin

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Chemistry of Natural Compounds Aims and scope

Abstract

The review gives methods of synthesizing the biocatalyst biotin. The existing methods of obtaining biotin and its stereoisomers from dihaloalkanes, dicarboxylic acid esters, sugars, thiophene derivatives, etc., are discussed. The basic possibilities of the formation of biotin are considered.

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  1. D. D. Mikhno
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  2. V. M. Berezovskii
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All-Union Scientific-Research Vitamin Institute. Translated from Khimiya Pridodnykh Soedinenii, No. 4, pp. 445–477, July–August, 1980.

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Mikhno, D.D., Berezovskii, V.M. Advances in the chemistry of biotin. Chem Nat Compd 16, 313–338 (1980). https://doi.org/10.1007/BF00568361

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