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Chemistry of Natural Compounds

, Volume 4, Issue 1, pp 22–24 | Cite as

Hydrolytic stability of the ester bond in aminoacyl derivatives of N-acetylglucosamine, glucosamine, and N-acetylneuraminic acid

  • V. A. Derevitskaya
  • V. M. Kalinevich
Article
  • 129 Downloads

Summary

The hydrolytic stability of the ester bond of O-aminoacyl derivatives of N-acetylglucosamine, glucosamine (base), and methyl N-acetylneuraminate has been studied at pH 1–8. It has been shown that the stability of the O-aminoacyl derivatives of N-acetylglucosamine is comparable with that of the corresponding glucose derivatives. The presence of a free amino group in glucosamine leads to a considerable labilization of the ester bond. The ester bond of the O-aminoacyl derivatives of methyl N-acetylneuraminate is characterized by a very high lability, and this must be taken into account in working with biopolymers.

Keywords

Glucosamine Ester Bond Amino Sugar Hydrolytic Stability Neuraminic Acid 

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References

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Copyright information

© The Faraday Press, Inc 1969

Authors and Affiliations

  • V. A. Derevitskaya
    • 1
  • V. M. Kalinevich
    • 1
  1. 1.Institute of the Chemistry of Natural Compounds, AS USSRUSSR

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