Chemistry of Natural Compounds

, Volume 2, Issue 2, pp 109–111 | Cite as

Cleavage of the peptide bonds in pepsin with cyanogen bromide

  • V. M. Stepanov
  • S. P. Katrukha
  • V. I. Ostoslavskaya
Article
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Summary

1. Conditions for the cyanogen bromide cleavage of the peptide bonds of pepsin formed by methionine have been found.

2. Pepsin contains a methionyl-valine bond and two methionyl-aspartic acid (or methionyl-asparagine) bonds.

Keywords

Peptide Bond Cyanogen Bromide Sodium Hydrogen Carbonate BrCN Porcine Pepsin 

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Copyright information

© The Faraday Press, Inc 1967

Authors and Affiliations

  • V. M. Stepanov
    • 1
  • S. P. Katrukha
    • 1
  • V. I. Ostoslavskaya
    • 1
  1. 1.Institute of the Chemistry of Natural Compounds, AS USSRUSSR

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