Chemistry of Natural Compounds

, Volume 11, Issue 1, pp 42–44 | Cite as

Synthesis of the hexapeptide L-phenylalanyl-L-prolyl-L-glutamyl-DL-phenylalanyl-L-valyl-L-leucine

  • L. V. Fedorova
  • L. G. Kovalenko
  • N. Ya. Krasnobrizhii


The synthesis of the γ,α-dimethyl ester of N-Cbo-L-phenylalanyl-L-prolyl-L-glutamyl-DL-phenylalanyl-L-valyl-L-leucine, not previously described in the literature, has been effected.


Ethyl Acetate Methyl Ester Hydrazide Hydrazine Hydrate Silver Nitrate 


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Literature cited

  1. 1.
    N. A. Poddubnaya and N. Ya. Krasnobrizhii, Zh. Obshch. Khim.,40, 1137, 1142 (1970);41, 567 (1971);42 949 (1972).Google Scholar
  2. 2.
    M. Bergmann. L. Zervas, and J. S. Fruton, J. Biol. Chem.,115, 593 (1936).Google Scholar
  3. 3.
    E. L. Smith, D. H. Spackman, and W. J. Polglase, J. Biol. Chem.,199, 801 (1952).PubMedGoogle Scholar
  4. 4.
    H. F. Schott, J. B. Larkin, L. B. Rockland, and M. S. Dunn, J. Org. Chem.,12, 490 (1947).CrossRefGoogle Scholar
  5. 5.
    R. A. Boissonnas, S. Guttman, P. A. Jaquenoud, and J. P. Waller, Helv. Chim. Acta.38, 1491 (1955).CrossRefGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1976

Authors and Affiliations

  • L. V. Fedorova
  • L. G. Kovalenko
  • N. Ya. Krasnobrizhii

There are no affiliations available

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