Summary
1. Peptides from tryptic hydrolysis of the cyanogen bromide fragments B-1 and B-2 of LSTH have been isolated and characterized.
2. The differences found in the amino-acid sequence of the individual peptides of fragment B of LSTH as compared with the corresponding sections of the O-LTH molecule are not due to species differences of the hormones.
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N. D. Gafurova, L. V. Nagornaya, and F. Yu. Ryshka, Khim. Prirodn. Soedin., 284 (1975).
A. M. Katz, W. J. Dreyer, and C. B. Anfinsen, J. Biol. Chem.,234, 2897 (1959).
C. H. Li, J. S. Dixon, T.-B. Lo, K. D. Schmidt, and Yu. A. Pankov, Arch. Biochem. Biophys.,141, 705 (1970).
F. Yu. Ryshka, L. V. Nagornaya, G. A. Zenkevich, Sh. A. Nasriddinov, and A. S. Khokhlov, Sovremennye Problemy Endocrinologii [in Russian], No. 4 (1972), p. 52.
P. Edman, Acta Chem. Scand.,4, 283 (1950).
W. Kônigsberg and R. T. Hill, J. Biol. Chem,234, 2547 (1962).
K. R. Woods and K. T. Wang, Biochem. Biophys. Acta,133, 369 (1967).
Yu. A. Pankov and G. P. Elizarova, Vopr. Med. Khim.,19, No. 3, 278 (1973).
B. K. Seavey and U. J. Lewis, Biochem. Biophys. Acta,42, 905 (1971).
V. Kostka and F. N. Carpenter, J. Biol. Chem.,239, 1799 (1964).
R. M. C. Dawson, D. E. Elliott, W. H. E. Elliott, K. M. Jones, Data for Biochemical Research, Oxford University Press, Oxford (1969), p. 525.
D. L. Spackman, W. H. Stein, and S. Moore, Analyt. Chem.,30, 1190 (1958).
J. Opienska-Blauth, M. Charezínsky, and H. Berbeć, Analyt. Biochem.,6, 69 (1963).
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All-Union Scientific-Research Institute of the Technology of Blood Substitutes and Hormone Preparations. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 502–507, July–August, 1975.
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Gafurova, N.D., Ryshka, F.Y. A study of the structure of lactosomatotropic hormone. Chem Nat Compd 11, 517–521 (1975). https://doi.org/10.1007/BF00566798
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DOI: https://doi.org/10.1007/BF00566798