Summary
A new method for the production of ω-(2, 4-dimethoxyphenyl)-resacetophenone, the basic intermediate in the synthesis of the phytoestrogen coumestrol by Emerson and Bickoff's method, has been described. The new variant of the production of this substance shortens the synthesis of coumestrol by a factor of 2. 7, 12-Diallyloxycoumestrol has been isomerized by a Claisen rearrangement into 8, 13-diallylcoumestrol.
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Khimiya Prirodnykh Soedinenii, Vol. 2, No. 1, pp. 51–55, 1966
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Shamshurin, A.A., Yampol'skaya, M.A. & Simonova, L.L. Phytoestrogens. Chem Nat Compd 2, 42–45 (1966). https://doi.org/10.1007/BF00566600
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DOI: https://doi.org/10.1007/BF00566600