Abstract
The structures of the products of the reduction of the antibiotic reumycin (I), which is a specific autooxidizable acceptor of reducing equivalents from certain flavin dehydrogenases of the respiratory chain of the mitochondria of yeast and animal tissues, have been established with the aid of physicochemical methods (UV, IR, and PMR spectroscopy and mass spectrometry). In the determination of the structures of five reduction products of reumycin effective use has been made of high-resolution mass spectrometry and a consideration of the spectra of metastable ions (the DADI technique). It has been shown that only the asym-triazine ring in the initial (I) undergoes reduction and ring-opening.
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All-Union Scientific-Research Institute of Antibiotics, Moscow Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 85–95, January–February, 1981.
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Esipov, S.E., Klyuev, N.A., Saburova, L.A. et al. A study of the products of the reduction of the antibiotic reumycin (6-methylpyrimido [5,4-e][1,2,4]triazine-5,7-dione). Chem Nat Compd 17, 76–85 (1981). https://doi.org/10.1007/BF00566439
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DOI: https://doi.org/10.1007/BF00566439