European Journal of Clinical Pharmacology

, Volume 13, Issue 6, pp 419–422 | Cite as

Dose response effect of bromazepam on psychomotor skills

  • I. Saario
  • T. Seppälä
Originals

Summary

The acute effects of bromazepam 1.5, 3, 6 and 12 mg on psychomotor skills were examined in 12 male volunteers. The two lower doses slightly improved psychomotor performance, probably due to reduction of tension. The 6 mg and especially the 12 mg dose impaired all the psychomotor factors tested. The impairment was roughly correlated with the increasing plasma levels 30, 90 and 150 min after administration of the drug. Psychomotor performance improved subsequently even if the plasma levels remained high.

Key words

Bromazepam psychomotor tests driving blood levels 

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Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • I. Saario
    • 1
  • T. Seppälä
    • 1
  1. 1.Department of PharmacologyUniversity of HelsinkiHelsinkiFinland

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