Summary
A comparative investigation of the inhibiting influence on transport Na+,K+-ATPase of four flavone aglycones and eight of their glycosides has been performed on the microsomal fraction of the cells of the cerebral cortex.
It has been shown that in concentrations of 1·10−4 to 5·10−6 M M myricetin, quercetin, luteolin, and myricetin 3′-glucoside possess an appreciable inhibiting effect. For kaempferol and its glycosides, as for the glycosides of quercetin and luteolin, the inhibiting effect is extremely feeble.
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Additional information
Institute of Biochemistry, Academy of Sciences of the Uzbek SSR, Tashkent. V. I. Lenin Tashkent State University. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 44–46, January–February, 1977.
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Mirsalikhova, N.M., Pakudina, Z.P. Flavonoid inhibitors of Na+,K+-ATPase. Chem Nat Compd 13, 37–39 (1977). https://doi.org/10.1007/BF00566166
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DOI: https://doi.org/10.1007/BF00566166