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Some laws of the polycondensation of activated esters of amino acids and peptides

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Summary

The polycondensation of activated esters (p-nitrophenyl, 2,4,6-trichlorophenyl, and pentachlorophenyl esters) of a number of amino acids and di- and tripeptides has been studied. The dependence of the degree of polymerization of the polypeptides on the time of polycondensation, on the initial concentration of monomer in the solution, and on the temperature has been established. The roles of the N- and C-terminal amino acids in the monomers in determining their capacity for polycondensation have been studied.

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V. I. Lenin Tadzhik State University. Institute of Molecular Biology, Academy of Sciences of the USSR. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 773–779, November–December, 1973.

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Zegel'man, A.B., Yusupov, T.Y., Khalikov, S.K. et al. Some laws of the polycondensation of activated esters of amino acids and peptides. Chem Nat Compd 9, 739–744 (1973). https://doi.org/10.1007/BF00565799

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