Influence of acetylation on the iodination of thyroglobulin and the formation of thyroxine
The results obtained show that when thyroglobulin is iodinatedin vitro the formation in it of thyroxine from the iodotyrosine residues present in it before iodination is possible. The structure of the thyroglobulin apparently plays an important role not only in the formation of thyroxine but also in the level of iodination of the protein.
KeywordsThyroxine Lysine Residue Thyroglobulin Arginine Residue Intact Protein
Unable to display preview. Download preview PDF.
- 1.Ya. Kh. Turakulov, T. A. Babaev, and T. Saatov, Iodoproteins of the Thyroid Gland [in Russian], Tashkent (1974).Google Scholar
- 3.E. E. Gussakovskii and T. A. Babaev, Abstracts of the Second All-Union Conference on the Spectroscopy of Biopolymers [in Russian], Khar'kov (1974), p. 40.Google Scholar
- 4.R. Lumry and R. Biltonen, in: Structure and Stability of Biological Macromolecules, (ed. S. N. Timasheff and G. Fasman), Marcel Dekker, New York (1969).Google Scholar
- 5.K. M. Ermolaev, N. A. Popova, and A. I. Tochilkin, Zh. Vses. Khim. O-Va.,14, 357 (1969).Google Scholar
- 6.V. L. Shiptsberg, T. N. Shaposhnikova, and K. M. Ermolaev, Khim. Prirodn. Soedin., 129 (1971).Google Scholar
- 8.T. A. Babaev, A. A. Avanesova, E. E. Gussakovskii, and T. Usmanov, Biokhimiya,37, 1306 (1972).Google Scholar
- 9.H. Edelhoch, J. Biol. Chem.,237, 2778 (1962).Google Scholar