Conclusions
The synthesis of evonoloside has been effected from cannogenol and L-rhamnose with a yield of 35%. It has been shown that when a primary alcohol group (at C19) and a secondary axial hydroxy group (at C3) are present in the aglycone, to introduce the sugar component at C3 it is desirable first to protect the primary OH group by the partial acetylation of the aglycone.
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References
S. G. Kislichenko, I. F. Makarevich, and D. G. Kolesnikov, KhPS [Chemistry of Natural Compounds], 2, 440, 1966.
S. G. Kislichenko, I. F. Makarevich, and D. G. Kolesnikov, KhPS [Chemistry of Natural Compounds], 3, 241, 1967.
W. Wehrli, Helv. Chim. Acta, 45, 1206, 1962.
I. F. Makarevich, KhPS [Chemistry of Natural Compounds], 3, 217, 1967.
I. F. Makarevich, KhPS [Chemistry of Natural Compounds], 4, 221, 1968.
F. Kaiser, Chem. Ber., 88, 556, 1955.
W. Königs and E. Knorr, Ber., 34, 957, 1901.
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Khimiya Prirodnykh Soedinenii, Vol. 5, No. 1, pp. 20–22, 1969
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Kislichenko, S.G., Makarevich, I.F. Partial synthesis of evonoloside. Chem Nat Compd 5, 15–16 (1969). https://doi.org/10.1007/BF00564911
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DOI: https://doi.org/10.1007/BF00564911