Chemistry of Natural Compounds

, Volume 7, Issue 4, pp 472–475 | Cite as

Synthesis of analogs of a tetrapepside of gastrin with a modified tryptophan residue

  • V. S. Vilka
  • G. I. Chipens


New derivatives of the COOH-terminal tetrapeptide of gastrin containing in place of the tryptophan residue the acyl radicals β-(1-naphthyl)acryloyl, β-(1-naphthyl)propionyl, β-(2-naphthyl)propionyl, and α-benzyloxycarbonylamino-β-(1-methylindol-3-yl)propionyl have been synthesized.


Methyl Ester Hydrazide Acryloyl Sodium Bicarbonate Solution Propionyl 


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Literature cited

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    I. S. Morley, F. Tracy, and R. A. Gregory, Nature,207, 1356 (1965).CrossRefGoogle Scholar
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    Z. A. Atare, V. S. Vilka, and G. I. Chipens, Khim. Prirodn. Soedin.,5, 283 (1969).Google Scholar
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    I. M. Davey, A. Laird, and F. S. Morley, J. Chem. Soc., (C),1966, 555.Google Scholar
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    G. I. Chipens, V. S. Vilka, and Z. A. Atare, Khim. Prirodn. Soedin.,6, 117 (1970).Google Scholar

Copyright information

© Consultants Bureau, a division of Plenum Publishing Corporation 1973

Authors and Affiliations

  • V. S. Vilka
  • G. I. Chipens

There are no affiliations available

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