Chemistry of Natural Compounds

, Volume 7, Issue 4, pp 421–424 | Cite as

Cardenolides of Gomphocarpus fruticosus and the partial synthesis of uzarigenin glycosides

  • V. T. Chernobai
  • N. F. Komissarenko


  1. 1.

    Six cardenolides have been isolated from the fermented leaves ofGomphocarpus fruticosus R. Br.: cardenolide 1, uzarigenin, gomphotin, and cardenolides 5, 6, and 7, and from the unfermented leaves, desglucouzarin.

  2. 2.

    From uzarigenin by partial synthesis desglucouzarin and a new glycoside — uzarigenin 3-O-α-L-rhamnopyranoside — have been obtained.



Glycoside Paper Chromatography Cardenolides Calcium Oxide Chromium Trioxide 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature cited

  1. 1.
    V. T. Chernobai, P. I. Bezruk, D. G. Kolesnikov, M. A. Angarskaya, Ya. I. Khadzhai, and M. P. Kozlovskaya, USSR Author's Certificate No. 164,415; Byul. Izobret., No. 15, 54 (1964).Google Scholar
  2. 2.
    T. R. Watson and S. E. Wright, Chem. Ind. (London), 1178 (1954); Aust. J. Chem.,9, 497 (1956);10, 79 (1957); R. G. Coombe, T. R. Watson, and R. M. Carman, Chem. Ind. (London), 1724 (1962); R. G. Coombe and T. R. Watson, Proc. Chem. Soc., 214, (1962); Austr. J. Chem.,17, 92 (1964); R. M. Carman, R. G. Coombe, and T. R. Watson, Aust. J. Chem.,17, 573 (1964).Google Scholar
  3. 3.
    V. T. Chernobai, Med. Prom. SSSR, No. 1, 38 (1957); V. T. Chernobai and D. G. Kolesnikov, Med. Prom. SSSR, No. 3, 29 (1957).Google Scholar
  4. 4.
    C. Djerassi, O. Halpern, V. Halpern, O. Schindler, and Ch. Tamm, Helv. Chim. Acta,41, 250 (1958).CrossRefGoogle Scholar
  5. 5.
    L. Masler, S. Bauer, O. Bauerova, and D. Sikl, Coll. Czech. Chem. Commun.,27, 872 (1962).CrossRefGoogle Scholar
  6. 6.
    J. M. Moore, Ch. Tamm, and T. Reichstein, Helv. Chim. Acta,37, 755 (1954).CrossRefGoogle Scholar
  7. 7.
    I. G. Zoz, N. F. Komissarenko, and N. A. Chernykh, Rast. Res.,4, 112 (1968).Google Scholar
  8. 8.
    G. Baumgarten, Die Herzwirksame Glykoside, G. Thieme, Leipzig (1963), p. 242; K. K. Chen, Proc. 1st Intern. Pharm. Meet.,3, 27 (1963).Google Scholar
  9. 9.
    H. Huber, F. Blindenbacher, K. Mohr, and B. Speiser, Helv. Chem. Acta,31, 64 (1951).Google Scholar

Copyright information

© Consultants Bureau, a division of Plenum Publishing Corporation 1973

Authors and Affiliations

  • V. T. Chernobai
  • N. F. Komissarenko

There are no affiliations available

Personalised recommendations