Chemistry of Natural Compounds

, Volume 8, Issue 6, pp 746–750 | Cite as

A study of the biosynthesis of colchicine and merenderine in Merendera raddeana

  • A. A. Trozyan
  • M. K. Yusupov
  • Kh. A. Aslanov
  • A. S. Sadykov


The biosynthesis of colchicine and merenderine inMerendera raddeana Rgl. has been studied.

The results of supplying the plants with [1-14C]phenylalanine, generally labeled tyrosine, and sodium [1-14C]acetate, and also of the degradation of the molecule of the colchicine isolated, have shown the general nature of the biosynthesis of this alkaloid in species of plants of the generaColchicum andMerendera Ram.

The inclusion of labeled tyrosine and phenylalanine in the merenderine molecul shows that the tropolone and nontropolone alkaloids ofMerendera have the same precursors but different biosynthetic routes.


Alkaloid Colchicine Succinic Acid Potassium Permanganate Caustic Soda 


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Copyright information

© Consultants Bureau 1974

Authors and Affiliations

  • A. A. Trozyan
  • M. K. Yusupov
  • Kh. A. Aslanov
  • A. S. Sadykov

There are no affiliations available

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