Chemistry of Natural Compounds

, Volume 10, Issue 4, pp 450–453 | Cite as

Coumarins of Ferula kopetdaghensis — Kopetdaghin and kopeodin (farnesiferol B)

  • Kh. M. Kamilov
  • G. K. Nikonov


From the roots ofFerula kopetdaghensis Eug. Kor. a new coumarin has been isolated which has been called kopetdaghin. On the basis of the hydrolysis products, the results of hydrogenation and acetylation, and spectroscopy, it has been established that kopetdaghin is an ether of 7-hydroxycoumarin and 1-(3-hydroxy-2,2,6-trimethylcyclohex-5-enyl)-3-methylpent-2-en-1-ol, i.e., an isomer of farnesiferol B.

Furthermore, farnesiferol B has been shown to consist of a natural mixture of kopetdaghin (30%) and a component with the structure previously proposed for it (70%).


Coumarin Methine Proton Olefinic Proton Umbelliferone Chromium Trioxide 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature cited

  1. 1.
    Kh. M. Kamilov and G. K. Nikonov, Khim. Prirodn. Soedin., 114 (1972).Google Scholar
  2. 2.
    P. I. Zakharov, V. S. Kabanov, M. E. Perel'son, A. I. Ban'kovskii, and N. E. Ermatov, Khim. Prirodn. Soedin., 296 (1970).Google Scholar
  3. 3.
    M. E. Perel'son, Yu. N. Sheinker, G. P. Syrova, G. K. Nikonov, and A. P. Prokopenko, in: Medicinal Plants [in Russian] (1960), pp. 15, 60.Google Scholar
  4. 4.
    Yu. N. Sheinker, Yu. G. Pek, and M. E. Perel'son, Dokl. Akad. Nauk SSSR,158, 1382 (1969).Google Scholar
  5. 5.
    G. K. Nikonov, Khim. Prirodn. Soedin., 572 (1971).Google Scholar
  6. 6.
    L. Caglioti, H. Naef, D. Arigoni, and O. Jeger, Helv. Chim. Acta,42, 2557 (1959).CrossRefGoogle Scholar

Copyright information

© Plemum Publishing Corporation 1976

Authors and Affiliations

  • Kh. M. Kamilov
  • G. K. Nikonov

There are no affiliations available

Personalised recommendations