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Granilin — A new lactone from Inula grandis

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Summary

From the epigeal part ofInula grandis Schrenk., collected in the rosette-incipient stem formation period, a new sesquiterpene lactone has been isolated with the formula C15H20O4, mp 197–198°C, [α] 25D +147.9° (acetone), and we have called it granilin. On the basis of the NMR spectra of the initial substance and the products of its hydrogenation and acetylation, it has been established that granilin has the most probable structure of 1,3-dihydroxyeudesma-4(14), 11(13)-dien-7,8-olide.

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Literature cited

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Authors
  1. L. P. Nikonova
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  2. G. K. Nikonov
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Additional information

Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR. Tashkent Pharmaceutical Institute. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 289–293, May–June, 1972.

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Nikonova, L.P., Nikonov, G.K. Granilin — A new lactone from Inula grandis. Chem Nat Compd 8, 286–289 (1972). https://doi.org/10.1007/BF00563730

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  • DOI: https://doi.org/10.1007/BF00563730

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