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Chemistry of Natural Compounds

, Volume 1, Issue 5, pp 269–272 | Cite as

Synthesis and properties of the methyl ester of polyuridylyl-(5′→ N)-phenylalanine

  • N. N. Preobrazhenskaya
  • N. I. Sokolova
  • Z. I. Shabarova
  • M. A. Prokof'ev
Article
  • 25 Downloads

Summary

1. The methyl ester of polyuridylyl-(5′→N)-phenylalanine containing an average of 13 nucleotide residues has been synthesized by the carbodiimide method.

2. The hydrolysis of the methyl ester of polyuridylyl-(5′→N)-phenylalanine has been studied as functions of pH and time. In this compound, the phosphoric amide bond is hydrolyzed in an acid medium and is stable at pH<4, and the half-period of hydrolysis of the phosphoric amide bond in 0.05 N hydrochloric acid solution is 20 min.

Keywords

Methyl Ester Phenylalanine Hydrochloric Acid Solution Caustic Potash Absolute Ether 

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Copyright information

© The Faraday Press, Inc 1966

Authors and Affiliations

  • N. N. Preobrazhenskaya
    • 1
  • N. I. Sokolova
    • 1
  • Z. I. Shabarova
    • 1
  • M. A. Prokof'ev
    • 1
  1. 1.Lomonosov Moscow State UniversityUSSR

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