Chemistry of Natural Compounds

, Volume 10, Issue 2, pp 216–218 | Cite as

Synthesis of regular polypeptides including lysine, proline, and alanine residues

  • L. I. Mar'yash
  • V. A. Shibnev


Polypeptides of the following sequences have been obtained: -Lys-Pro-,-Lys2-Pro-, -Lys3-Pro-,-Lys-Pro2-, and -Lys-Ala-, with molecular weights of from 1000 to 14,000. It has been established that the use of pentachlorophenyl esters for polymerization in place of 2,4,5-trichlorophenyl esters leads to a considerable increase in the molecular weights of the polypeptides.


HCOOH DMFA Alanine Residue Benzyloxycarbonyl Ethyl Acetate Solution 


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Literature cited

  1. 1.
    D. M. P. Phillips (Editor), Histones and Nucleohistones, Plenum (1971).Google Scholar
  2. 2.
    K. T. Poroshin, V. K. Burichenko, L. I. Mar'yash, and V. S. Shibnev, Izv. Akad. Nauk SSSR, Ser. Khim., 1276 (1971).Google Scholar

Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • L. I. Mar'yash
  • V. A. Shibnev

There are no affiliations available

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