Chemistry of Natural Compounds

, Volume 10, Issue 2, pp 193–195 | Cite as

NMR spectra of dihydrogalanthamine and dihydroepigalanthamine and of their acetyl derivatives

  • M. R. Yagudaev
  • A. Abdusamatov
  • S. Yu. Yunusov
Article
  • 19 Downloads

Conclusions

1. On the basis of the results of a comparative study of the NMR spectra of dihydrogalanthamine and dihydroepigalanthamine and their acetyl derivatives it has been shown that in the hydrogenation of the C2-C3 double bond of galanthamine and its analog a diamagnetic shift of the i and C1-H protons by 0.35 and 0.25–0.60 ppm, respectively, take place.

2. The anomalous nature of the CSs of theae C1-H protons in these compounds is due to the substantial influence on their magnetic anisotropy and electric field of the unshared pair of electrons of the O atom and the C-O bond of ring C.

Keywords

Magnetic Anisotropy Dihydro Acetyl Derivative Galanthamine Dihydrofuran 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature cited

  1. 1.
    M. R. Yagudaev, A. A. Abdusamatov, and S. Yu. Yunusov, Khim. Prirodn. Soedin., 235 (1970).Google Scholar
  2. 2.
    L. M. Jackman, Applications of NMR Spectroscopy in Organic Chemistry, 1st ed., Pergamon (1959).Google Scholar
  3. 3.
    N. Bhacca and D. Williams, Applications of NMR Spectroscopy in Organic Chemistry, Holden-Day (1964).Google Scholar
  4. 4.
    H. M. McConnell, J. Chem. Phys.,27, 226 (1957).CrossRefGoogle Scholar
  5. 5.
    A. D. Buckingham, Can. J. Chem.,38, 300 (1960).CrossRefGoogle Scholar
  6. 6.
    R. F. Zürcher, Progr. Nucl. Mag. Res. Spectrosc.,2 (1967).Google Scholar
  7. 7.
    A. V. Bogat-skii, Yu. Yu. Samitov, N. L. Garkovik, and S. A. Andronati, Khim. Geterotsikl. Soedin., No. 2, 195 (1967).Google Scholar
  8. 8.
    F. A. L. Anet and M. Z. Haq, J. Am. Chem. Soc.,87, 3147 (1965).CrossRefGoogle Scholar
  9. 9.
    N. F. Proskurnina and A. P. Yakovleva, Zh. Obshch. Khim.,22, 1899 (1952).Google Scholar

Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • M. R. Yagudaev
  • A. Abdusamatov
  • S. Yu. Yunusov

There are no affiliations available

Personalised recommendations