Summary
A simple practical and reliable method for the determination of the iron content in skin sections obtained by punch biopsy is developed for diagnostie and follow-up studies.
The mean value of the iron content in the chest-wall skin of normal persons is 65 ± 25 µmol Fe/100 g dry weight.
In cases of haemochromatosis and symptomatic porphyria cutanea tarda the iron content of the skin is significantly increased.
Zusammenfassung
Zur Bestimmung des Eisengehaltes in histologisch verarbeiteten Hautstanzen ist eine einfache, praktische und zuverlässige Methode entwickelt worden. Der durchschnittliche Eisengehalt in der normalen menschlichen Brusthaut beträgt 65 ± 25 µmol Fe/100 g Trockengewicht. Bei Patienten mit Haemochromatose und symptomatischer Porphyria cutanea tarda ist der Eisengehalt der Haut signifikant erhöht.
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van Eijk, H.G., Tio, T.H. & Bos, G. Iron in skin biopsies. Arch. Derm. Res. 251, 245–248 (1975). https://doi.org/10.1007/BF00561766
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DOI: https://doi.org/10.1007/BF00561766