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Surface lipid estimation on the back of the hands in atopic dermatitis

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Summary

Skin surface lipids were estimated on the uninvolved skin of the back of hands in patients with atopic dermatitis by a gravimetric method and a significant decrease was found. According to results of thin layer chromatographic studies recorded by densitometry, this lipid reduction is due to a decrease in skin lipids of sebaceous origin. The low sebum excretion on the hands in atopic dermatitis is in agreement with clinical observations of frequent dryness of the skin in this region.

Zusammenfassung

Hautoberflächenlipide wurden in der unveränderten Haut des Handrückens bei atopischem Ekzem mit einer gravimetrischen Methode gemessen. Eine signifikante Verminderung wurde festgestellt.

Ergebnisse chromatographischer Untersuchungen mit Densitometrie zeigten, daß diese Lipidverminderung durch eine Verminderung der Talgdrüsenlipide verursacht wird. Die niedrigen Talgabsonderungen an Händen bei atopischem Ekzem stimmt mit klinischen Beobachtungen von häufig trockener Haut in diesen Hautgebieten überein.

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Authors and Affiliations

  1. Derm. Dept. Rikshospitalet, University of Oslo, Norway

    Georg Rajka

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  1. Georg Rajka
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Rajka, G. Surface lipid estimation on the back of the hands in atopic dermatitis. Arch. Derm. Forsch. 251, 43–48 (1974). https://doi.org/10.1007/BF00561709

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