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Porphyria cutanes tarda: Normalisierung der porphyrin-ausscheidung unter p-aminobenzoat (potaba®)

Porphyria cutanea tarda: Normalization of porphyrin-excretion following treatment with p-amino-benzoic acid (potaba®)

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Summary

Two patients with porphyria cutanea tarda were treated with p-amino-benzoic acid (Potaba®) (3 × 4 g/day).

Normalization of porphyrin-excretion was observed after three respectively 45 days of treatment. Furthermore no influence of the excretion of porphyrin precursors (porphobilinogen or delta-amino-levulinic acid) were noticed. Also, no side effects of this treatment were found.

Zusammenfassung

Es wird über zwei Patienten mit dem klinischen und biochemischen Vollbild der Porphyria cutanea tarda berichtet, bei denen es nach Behandlung mit 3 × 4 g p-Aminobenzoat (Potaba®) innerhalb von 45 bzw. 3 Tagen zu einer quantitativen und qualitativen Normalisierung der Porphyrin, Ausscheidung kam. Eine Beeinflussung der Ausscheidung an 5-Aminolaevulinsäure und Porphobilinogen erfolgte nicht. Nebenwirkungen wurden unter dieser Behandlung nicht beobachtet.

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Authors and Affiliations

  1. Universitäts-Hautklinik, Moorenstraße 5, D-4000, Düsseldorf, Germany

    G. Goerz, Th. Krieg & K. Bolsen

Authors
  1. G. Goerz
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  2. Th. Krieg
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  3. K. Bolsen
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Goerz, G., Krieg, T. & Bolsen, K. Porphyria cutanes tarda: Normalisierung der porphyrin-ausscheidung unter p-aminobenzoat (potaba®). Arch. Derm. Res. 255, 331–335 (1976). https://doi.org/10.1007/BF00561503

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  • DOI: https://doi.org/10.1007/BF00561503

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