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Biochemical Genetics

, Volume 26, Issue 3–4, pp 207–211 | Cite as

Nucleotide sequence of the humanθ1-globin gene

  • J. M. Gonzalez-Redondo
  • I. S. Han
  • Y. -C. Gu
  • T. H. J. Huisman
Article

Abstract

We have cloned and sequenced the human θ1-globin gene. The nucleotide sequence and organization of the human θ1 gene (exons, introns, promoter, and polyadenylation signals) are similar to those reported for the orangutan θ1-globin gene. If these genes are functional, the sequences of their θ1-globin chains would differ by only one amino acid residue (at position 137).

Key words

DNA sequence human θ1-globin gene cloning 

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Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • J. M. Gonzalez-Redondo
    • 1
  • I. S. Han
    • 1
  • Y. -C. Gu
    • 1
  • T. H. J. Huisman
    • 1
  1. 1.Department of Cell and Molecular BiologyMedical College of GeorgiaAugusta

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