European Journal of Clinical Pharmacology

, Volume 4, Issue 3, pp 158–161 | Cite as

Plasma concentrations of cardiac glycosides in digitalis intoxication

  • G. Somogyi
  • A. Káldor
  • A. Jankovics


Using the method of Löwenstein and Corrill modified by the authors the relationship between measured plasma digitalis concentrations and symptoms and signs of toxicity was studied in cases of suicide and accidental poisoning. Direct relationship could not be detected between plasma levels and clinical symptoms. Severe toxic symptoms occured only in the presence of high levels. Nevertheless, patients with high plasma levels may be symptom-free. Parallelism was observed between a fall in the digitalis level and the disappearance of clinical symptoms.

Key words

Digitalis intoxication digoxin assay suicide forensic 


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Copyright information

© Springer-Verlag 1972

Authors and Affiliations

  • G. Somogyi
    • 1
    • 2
  • A. Káldor
    • 1
    • 2
  • A. Jankovics
    • 1
    • 2
  1. 1.2nd Medical Department of the Semmelweis University Medical SchoolBudapestHungary
  2. 2.the Traumatologic Medical Department of the Korányi Frigyes and Korányi Sándor HospitalBudapestHungary

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