Summary
The ultrastructure of lipid droplets of sebaceous carcinoma (Meibomian gland carcinoma) was studied by conventional methods and a lipid-retention procedure. Two different structures were clearly differentiated by the latter technique. The peripheral part of the lipid droplet was composed of whirled lamellar structures (myelin-like structures) while the interior appeared to be continuously homogenous. The lamellar structures were presumed to have come from smooth-surfaced endoplasmic reticulum, and to transform to the amorphous material—triglyceride—during maturation of the lipid droplets.
A true limiting membrane or membranous shell around the lipid droplet was not deceted.
Zusammenfassung
Die Ultrastruktur der Lipidtropfen eines Carcinoms der Meibomianschen Drüsen wurde mittels konventioneller Methoden und einer Lipid-Retentionstechnik untersucht. Zwei unterschiedliche Strukturen ließen sich durch die letzte Technik klar herausarbeiten. Der periphere Teil der Lipidtropfen bestand aus wirbelförmigen lamellären Strukturen (myelinähnlichen Strukturen), während das Zentrum des Tropfens homogen erschien. Es wird angenommen, daß die lamellären Strukturen sich von dem endoplasmatischen Reticulum ableiten und sich während der Reifung der Lipidtropfen zu einem amorphen Material (Triglyceride) transformieren. Ein abschließendes Membran um die Lipidtropfen wurde nicht beobachtet.
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Niizuma, K. Lipid Droplet of Sebaceous Carcinoma. Arch. Derm. Res. 260, 111–119 (1977). https://doi.org/10.1007/BF00561116
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DOI: https://doi.org/10.1007/BF00561116